Trimethyl Glycene is a substance that is used in many different over the counter supplements, including those in the diet pill industry. It is an ingredient that is quite commonplace and that may be identified as any of many different possible names.
Among the names typically used as alternatives to trimethyl glycine include: oxyneurine, TMG, betaine anhydrous, trimethylglycine anhydrous, trimethylglycine, lycine and others. No matter how it may be named on a product label, the way it works and the types of effects it has within the body are the same as they would be if the product simply calls it trimethyl glycene.
As much as the name of this ingredient may sound like a complicated chemical, it is a naturally derived substance. It is a type of natural chemical found within the human body and that can be extracted from several common forms of food, such as seafood, cereals, beets, spinach, and even a typical bottle of wine.
The U.S. Food and Drug Administration (FDA) has given its approval for the use of this ingredient for a number of purposes. Among them include the treatment of a condition called homocystinuria, in which trimethyl glycene can help to treat elevated urine homocysteine levels. This can be important for some individuals who have certain genetic disorders as well as among some patients with skeletal issues, osteoporosis, eye lens issues and some forms of heart disease.
That said, trimethyl glycene is also used for a range of other purposes, including liver disease treatment, athletic performance improvement, immune system support, osteoarthritis, congestive heart failure, blood homocysteine lowering and obesity, among others. That said, those uses are not yet approved by the FDA.
Trimethyl glycene works within the human body by altering homocysteine metabolism. This can alter many other factors within the body including blood makeup, bone density and even parts of the nerves, heart, eyes and brain. Beyond impacting homocysteine levels in the body – and possibly decreasing the sensation of dry mouth when used in certain oral care products – most other uses of this ingredient do not have enough medical evidence to consider them to be proven.
The majority of the research conducted on this ingredient has been limited and preliminary. While it is often used for treating obesity, particularly in supporting the exercise component of a healthy weight loss diet, any benefits for that purpose are not yet proven by reputable research.